Massive Cavitation by Pneumocystis jirovecii in an Immunocompromised Patient.

Since the development of antiretroviral therapy (ART) and antibiotic prophylaxis, the incidence of opportunistic infections in human immunodeficiency virus-acquired immunodeficiency syndrome (HIV-AIDS) has been drastically reduced. However, third-world countries remain a fertile ground for medication nonadherence and inappropriate patient follow-up. Here, we present the case of a 42-year-old male with a history of HIV who presented with worsening shortness of breath and atypical chest pain. A chest X-ray and chest computed tomography scan revealed a left parahilar cavitation measuring 86 mm in diameter. A percutaneous lung biopsy revealed Pneumocystis jirovecii. Appropriate antibiotics were started, and the patient's clinical status significantly improved. This case illustrates the devastating consequences of uncontrolled HIV-AIDS. ART and prophylactic antibiotics remain the cornerstone of treatment to ameliorate progressive lung damage in patients.

Recurrent Steven-Johnson/Toxic Epidermal Necrolysis Overlap Syndrome.

Steven-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening mucocutaneous reactions that are predominantly drug-induced. Treatment varies depending on the severity, but even with accurate medical management, the mortality rate can be up to 50% in severe cases. Recurrent episodes with different agents are uncommon, but they have been reported in the literature. We present a case of a 30-year-old female presenting with recurrent SJS/TEN overlap syndrome complicated by sepsis after phenytoin use. Records revealed a previous episode after carbamazepine use one month prior to the current presentation and a first episode 23 years ago with an unknown medication. The offending agent was discontinued, the appropriate treatment was given, and the patient's clinical status significantly improved. This case highlights the life-threatening manifestation of a mucocutaneous reaction. Prompt clinical assessment is paramount for patient survival.

Autopercepción de la salud según lugar de residencia en trabajadores de ocho países de Latinoamérica / Health self-perception according place of residence in workers from eight Latin American countries

Objetivo: Determinar la autopercepción de la salud de los trabajadores según el lugar de residencia en ocho países de América Latina. Material y Métodos: Investigación analítica transversal, se preguntó por la autopercepción de la salud física, mental y de la satisfacción laboral. Se encontró estadísticos de asociación con los modelos lineales generalizados. Resultados: De los 3185 trabajadores que respondieron, el 23%, 20% y 13% percibieron que tenían muy buena satisfacción laboral, salud mental y salud física, respectivamente. En el análisis multivariado, a comparación del país de Venezuela, percibieron una menor frecuencia de mala salud mental el Perú, Ecuador, Honduras y Panamá; la salud física fue mejor percibida por Colombia y Panamá y peor percibida por Honduras, Argentina y Bolivia; la satisfacción laboral fue mejor percibida por Perú y Panamá. Conclusión: Si bien los porcentajes de adecuada salud física y mental fueron altos. La inadecuada percepción de ellos estuvo más en algunos países siendo indicadores que deben ser tomados en cuenta para mejorar la salud colectiva (AU)

Objective: Determine the self-perception of workers’ health according to place of residence in eight Latin American countries. Material and Methods: Cross-sectional analytical research, asked about self-perception of physical, mental health and job satisfaction. We found association statistics with generalized linear models. Results: Of the 3185 workers who responded, 23%, 20% and 13% perceived that they had very good job satisfaction, mental health and physical health, respectively. In the multivariate analysis, compared to the country of Venezuela, they perceived a lower frequency of mental ill health in Peru, Ecuador, Honduras and Panama; Physical health was better perceived by Colombia and Panama and worse perceived by Honduras, Argentina and Bolivia; Labor satisfaction was better perceived by Peru and Panama. Conclusion: Although the percentages of adequate physical and mental health were high. The inadequate perception of them was more in some countries. These are indicators that must be taken into account to improve collective health (AU)